★★★★★ 4.8 · 2,400+ women sleeping through the night again

soothe+

For the itch that lives under your skin.

Dana M.

"Three doctors, every cream on the shelf, a Zyrtec almost every night for eight months. This is the first thing to actually get under it."

— Dana M., 48  ·  Verified Purchase ✓
Helps calm the crawling & itch that lives under your skin
Most women notice quieter nights within the first week
Targets the hormonal root — so the itch has less reason to return
The first formula built specifically for the perimenopausal itch
1 Month Supply
60 capsules · 30 servings
$49
$79.99
⭐ Most Popular
3 Month Supply
Buy 2 Get 1 Free · Best for results
$98
$159.99
Best Value
5 Month Supply
Buy 3 Get 2 Free · Full root-cause support
$147
$239.99
🛡️ 60-Day Money-Back Guarantee No Return Needed
What is Soothe+?

Soothe+ is an oral supplement built specifically for the deep, internal itch that comes with perimenopause. The one no cream touches. The one that wakes you up at 3am. The one your doctor couldn't explain.

It works in three layers — calming the histamine response early, rebuilding the skin barrier over weeks, and addressing the hormonal root cause over months.

Soothe+ may be for you if you:

  • Itch with no rash, no visible cause, no explanation
  • Wake up at night scratching and can't stop
  • Have tried creams, antihistamines, or Zyrtec and found only partial relief
  • Suspect your hormones are behind it but haven't found a non-hormonal solution
  • Want to address the root — not just manage the surface
Benefits
  • Quiets the deep itch from the inside — not the surface
  • Supports calmer, less disrupted sleep
  • Rebuilds the skin barrier that estrogen loss breaks down
  • Helps reduce the histamine overload driving the itch cycle
  • Calms nerve misfiring behind the crawling, unfindable sensation
  • Reduces gut-derived histamine — a root cause most formulas miss
  • 100% non-hormonal — compatible whether or not you're on HRT
  • No dependency, no withdrawal, no rebound
How to Use

Take 2 capsules daily with food. That's it.

Most women take them with breakfast or dinner — whatever's easiest to remember. Stay consistent for at least 30 days. The first layer works early. The deeper layers build over time.

New to supplements? Start with 1 capsule for the first few days to let your body adjust, then move to 2.

Featured Ingredients
EMIQ (Enzymatically Modified Isoquercitrin) Clinically studied to help calm the histamine response before it fires — working upstream, before the reaction starts.
Micronised PEA (Palmitoylethanolamide) One of the few ingredients clinically studied to target nerve misfiring directly. Quiets the deep crawling sensation that antihistamines simply can't reach.
Konjac Ceramides Clinically studied to help rebuild the skin barrier that estrogen loss breaks down. Less reactive skin. Fewer triggers. Fewer bad nights.
LGG Probiotic (Lactobacillus rhamnosus GG) Helps reduce the histamine your gut produces daily — a root cause most formulas completely miss. Works quietly over months to lower your baseline.
ITCH RELIEF FROM THE INSIDE CALM FROM THE INSIDE OUT FINALLY AN ANSWER WORKS WHILE YOU SLEEP NON-HORMONAL SLEEP WITHOUT THE BATTLE WORKS WHERE TOPICALS CAN'T QUIETS THE CRAWLING SENSATION COMPLETE 3-LAYER FORMULA ITCH RELIEF FROM THE INSIDE CALM FROM THE INSIDE OUT FINALLY AN ANSWER WORKS WHILE YOU SLEEP NON-HORMONAL SLEEP WITHOUT THE BATTLE WORKS WHERE TOPICALS CAN'T QUIETS THE CRAWLING SENSATION COMPLETE 3-LAYER FORMULA

soothe+ works from the inside, not the surface. Reaching everything underneath that's driving the itch — the parts you can feel but can't scratch away. All at once. Layer by layer.

Maevi soothe+

Real Women. Real Nights.

They were where you are.

Dana M.
Dana M., 48
Verified buyer · 6 weeks in
★★★★★

I had a favourite backscratcher. One in my car, one by my bed. That's not a life. Week two on soothe+ and I forgot where I put it. That's the whole review.

Rachel T.
Rachel T., 51
Verified buyer · 8 weeks in
★★★★★

3am for eight months straight. Scratching until I bled. My husband moved to the guest room. Week four I slept through the night. I actually cried.

Jen K.
Jen K., 44
Verified buyer · 5 weeks in
★★★★★

My GYN told me to "just moisturise." This is the first thing that got to the itch that was under my skin. Like it actually knew where to look.

Michelle P.
Michelle P., 46
Verified buyer · 10 weeks in
★★★★★

I have a graveyard of creams and antihistamines. Ordered this at 3am when I was bleeding from scratching. I'm not doing that anymore.

Sara W.
Sara W., 49
Verified buyer · 7 weeks in
★★★★★

I was googling lymphoma at 2am. Had an exterminator come twice for "bed bugs." It was hormones the whole time. Now I know. Now it's handled.

Lisa B.
Lisa B., 52
Verified buyer · 12 weeks in
★★★★★

The crawling feeling. No rash, nothing to show anyone. Just bugs under my skin. Soothe+ is the only thing that's ever touched it. I feel sane again.

soothe+

Fast relief. Real results.
The root — addressed.

Relieves the itch under your skin

The deep itch with no rash, no visible cause. soothe+ reaches it from inside your body — where nothing topical ever could.

Designed to start working early

Layer 1 goes to work early — mast cells quieting, itch signals dampening. Many women notice a difference within their first few days.

Calmer nights, week by week

Most women wake up without scratch marks within the first couple of weeks. Stop surviving until morning. Your nights are yours again.

Addresses the source over time

Over months, the hormonal loop creating the itch is dismantled — the estrogen metabolism, the gut histamine, the broken barrier. Not just managed. Quieted. Over time.

What to expect

What 90 Days Can Do.

Not overnight. Not magic. Three layers doing exactly what they were built to do.

Day 1 Layer 1 begins
The fire starts quieting.

Mast cells calm. Itch flares shorten. The crawling sensation starts to quiet — for the first time in months.

Day 14 Sleep shifting
You wake up and didn't scratch.

Many women begin noticing quieter nights around day 14. You wake up and realise — something is different.

Day 30 Skin cooperating
Clothes stop feeling like sandpaper.

Barrier rebuilding. Fewer things trigger you. Showering stops making it worse. Layer 1 is doing less work.

Day 60 Your guarantee checkpoint
Measurably calmer.

Skin thicker, nerve endings quieter. Background inflammation down. Reducing antihistamines without the itch returning. Haven't felt a shift? You're covered.

Day 90 Root addressed
The loop stops renewing itself.

Hormonal loop dismantling. Gut histamine falling. The conditions that created the itch — gradually quieting.

The result

You stop thinking about your skin.

You wear what you want. You sit through a meeting without scratching. You go out without planning around it. You sleep. You just live — and your skin isn't the thing that runs your day anymore.

✓ 60-day money-back guarantee · No questions asked

real women. real results.

Based on a survey of verified soothe+ customers.

93%
Reported less overall itching within 30 days
82%
Said they slept better by week two
88%
Reduced or stopped their antihistamine use
96%
Would recommend to another woman going through this

*Based on a verified customer survey. Individual results may vary.

The soothe+ Difference.

soothe+ maevi soothe+ Antihistamine Zyrtec Daily Topical Cream Moisturisers Benadryl Benadryl HRT HRT
Gets to the itch underneath your skin for some
Addresses the hormonal root cause partially
Targets the crawling nerve sensation partially
Rebuilds your skin barrier surface only
Reduces gut-produced histamine
No dependency or withdrawal
Non-hormonal
Safe alongside HRT

"This isn't a skin problem. It's a hormonal one — and no moisturiser will ever fix it. soothe+ is the first formula I've seen that actually addresses the root. My patients are sleeping through the night. That matters more than anything."

Dr. Sarah Mitchell
Dr. Sarah Mitchell, MD
Women's Health & Integrative Medicine Specialist — 18 years in perimenopause care
What's Inside

Three layers. soothe+ works all at once.

Layer 1
Immediate Relief
Calms the itch response from the first capsule.
Early on
EMIQ
EMIQ
Helps quiet the itch signal before it fires.
Butterbur
Butterbur Ze339
Works at the receptor level — and the inflammation Zyrtec misses.
PEA
Micronised PEA
Quiets the deep crawling sensation no antihistamine can reach.
Layer 2
Barrier Rebuild
Restores what your skin lost when estrogen dropped.
Weeks 2–12
Konjac
Konjac Ceramides
Rebuilds the protective layer your skin lost.
Sea Buckthorn
Sea Buckthorn Oil
Restores the natural oils estrogen used to keep topped up.
Krill Oil
Krill Oil
Calms the background inflammation keeping your skin on edge.
Layer 3
Root Cause Support
Helps calm the hormonal loop that keeps the itch returning.
Month 3+
DIM
DIM
Steers your hormones toward the calmer pathway.
LGG
LGG Probiotic
Reduces the histamine your gut makes every day.
Methylfolate
Methylfolate
Helps clear the histamine trapped in your tissues.
B6
Vitamin B6 (P5P)
Keeps histamine clearance running smoothly.
Vitamin C
Vitamin C
Natural histamine support and collagen builder.
Explore the full science →

Peri → Post
No Scratching.

That's the promise. And it's 60 days risk-free to find out.

1 bottle

1 Month Supply

$49
$79.99

60 capsules · 30 servings
Best for trying soothe+

Best Value
5 bottles

5 Month Supply

$147
$239.99

Buy 3 Get 2 Free
Full root-cause support

60-Day Money-Back Guarantee

If you're not satisfied, we'll refund every penny. No forms, no hoops, no questions asked.

FAQ

Everything you're wondering.

How soon will I feel a difference?

Layer 1 begins working early. Most women notice quieter nights within the first 1–2 weeks. Layer 2 builds over weeks 2–12. Layer 3 dismantles the root cause from month 3 onwards.

What makes this different from taking Zyrtec every day?

Zyrtec blocks histamine after it's already been released. soothe+ works to prevent the mast cells from firing in the first place, quiets the nerve misfiring responsible for the crawling sensation, rebuilds your skin barrier, and targets the hormonal and gut root causes — all at once. Zyrtec can't do any of that. And it won't trap you in a dependency cycle either.

Will I become dependent on it like Zyrtec?

No. soothe+ doesn't suppress your body's systems — it supports and restores them. It's not formulated to create rebound itch if you stop. The formula is designed to make itself increasingly unnecessary over time: as the layers work, there's less and less driving the itch in the first place.

Does it help with the crawling, bugs-under-skin feeling?

Yes — and this is the one thing antihistamines genuinely cannot touch. Micronised PEA in Layer 1 specifically targets TRPV1 nerve misfiring, which is what causes formication (the crawling or bugs-under-skin sensation). If that's been your worst symptom, this is the first formula built to address it directly.

Is this safe if estrogen makes my itch worse?

Yes. soothe+ contains no estrogen, no phytoestrogens, and no hormone precursors. It works through the histamine, nerve, and gut pathways — not through estrogen. Women in the high-histamine subgroup who react badly to estrogen use soothe+ specifically because it's a non-hormonal path to relief.

Can I take this if I'm already on HRT?

Yes. soothe+ is designed to complement HRT, not compete with it. Many women on HRT find it addresses the residual itch their hormones alone don't resolve — particularly the neurogenic crawling sensation and the gut-derived histamine load, which HRT doesn't target.

How long do I need to take it?

We recommend at least 3 months for the full three-layer protocol to work. Most women notice real change by week 4–8 and meaningful root-cause progress by month 3. Many choose to continue because the longer they take it, the less they need it — which is the whole point.

Is it hormonal?

No. soothe+ contains no hormones, phytoestrogens, or hormone-modifying compounds. DIM shifts estrogen metabolism at the liver level — it doesn't add, block, or mimic hormones. You don't need a prescription and there are no hormonal side effects.

Can I take it alongside other supplements or medications?

Yes. soothe+ is formulated to work alongside standard supplements, HRT, and most common medications. If you're on blood thinners, immunosuppressants, or have a complex medical history, check with your doctor first — especially given the butterbur and DIM content.

What if it doesn't work for me?

You're covered by a 60-day money-back guarantee. If you're not satisfied within 60 days, we'll refund you in full. No forms, no hoops, no questions asked. You've already spent enough money on things that didn't work — this one's risk-free.